Poor results for everolimus in patients with liver cancer

The Lancet Oncology, Volume 15, Issue 9, Page e368, August 2014

doi:10.1016/S1470-2045(14)70318-3Cite or Link Using DOI

Published Online: 11 July 2014

Copyright © 2014 Elsevier Ltd All rights reserved.

Poor results for everolimus in patients with liver cancer

Talha Khan Burki

Everolimus is ineffective in treating patients with advanced hepatocellular carcinoma who are either refractory to or intolerant of sorafenib, according to a phase 3 study . The randomised trial of 546 patients (362 assigned to everolimus and 184 to placebo) showed that the mTOR inhibitor offered no survival benefit. 303 (84%) patients died in the everolimus group compared with 151 (82%) in the placebo group (hazard ratio [HR ] 1·05, 95% CI 0·86—1·27; p=0·68).

The Truth About Chemotherapy

If you asked oncologists what they really think of cancer treatments, you’d be shocked.

According to one report, when a leading doctor at the Sloan-Kettering Cancer Center found out that he had advanced-stage cancer, he told his colleagues, “Do anything you want—but no chemotherapy!”

And he’s not alone. Another official reportedly refused to allow his mother to undergo “state-of-the-art” therapy at his own hospital. What did he do? He sent her to Germany for “alternative” care.

But it’s not surprising when you consider the side effects of traditional treatment…hair loss, nausea, fatigue, cancer even!
To Your Health,
Charlie Foster,
Research Manager
The Institute for Natural Healing

Chain smoker’s widow awarded RM73.6 billion in damages

A Florida jury has awarded the widow of a chain smoker who died of lung cancer 18 years ago record punitive damages of more than US$23 billion (RM73. 6 billion) in her lawsuit against the R.J. Reynolds Tobacco Company, the nation’s second-biggest cigarette maker.

The judgement, returned on Friday night, was the largest in Florida history in a wrongful death lawsuit filed by a single plaintiff, according to Ryan Julison, a spokesman for the woman’s lawyer, Chris Chestnut.

Cynthia Robinson of the Florida Panhandle city of Pensacola sued the cigarette maker in 2008 over the death of her husband, Michael Johnson, claiming the company conspired to conceal the health dangers and addictive nature of its products.

Johnson, a hotel shuttle bus driver who died of lung cancer in 1996 at age 36, smoked one to three packs a day for more 20 years, starting at age 13, Chestnut said.

“He couldn’t quit. He was smoking the day he died,” the lawyer told Reuters on Saturday.
Read more: http://www.therakyatpost.com/world/2014/07/20/chain-smokers-widow-awarded-rm73-6-billion-damages/#ixzz3806mLIvi

Study Discounts Testosterone Therapy for Early Prostate Cancer

For decades, millions of men with early prostate cancer have been placed on drug therapy to suppress their production of testosterone, despite such significant side effects as impotence, diabetes and bone loss. Now a large new analysis has concluded that so-called androgen deprivation therapy does not extend the lives of these patients.

“There are so many side effects associated with this therapy, and really little evidence to support its use,” said Dr. Grace L. Lu-Yao, a researcher at the Rutgers Cancer Institute of New Jersey and the lead author of the report, published on Monday in JAMA Internal Medicine. “I would say that for the majority of patients with localized prostate cancer, this is not a good option.”

Read more: http://well.blogs.nytimes.com/2014/07/14/study-discounts-testosterone-therapy-for-early-prostate-cancer/?_php=true&_type=blogs&_php=true&_type=blogs&_php=true&_type=blogs&module=Search&mabReward=relbias%3Ar%2C%7B%221%22%3A%22RI%3A6%22%7D&_r=2&