Why Most Published Research Findings Are False

John P. A. Ioannidis is in the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, and Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, United States of America.

Dr. Ioannidis wrote:

  • There is increasing concern that in modern research, false findings may be the majority or even the vast majority of published research claims. This should not be surprising. It can be proven that most claimed research findings are false. ·
  • Most research findings are false for most research designs and for most fields.
  • Claimed research findings may often be simply accurate measures of the prevailing bias.

Click here to read more: PLoS Med. 2005 August; 2(8): e124

Lies, Damned Lies and Medical Science

The author wrote about Dr. John Ioannidis, M.D., Ph.D., undoubtedly one of the world’s foremost experts on the credibility of medical research.  Dr. Ioannidis spent his career challenging his peers by exposing their bad science. This outstanding scientist was born in New York in 1965 but grew up in Athens, Greece.

Dr. Ioannidis is a Professor in the Department of Hygiene & Epidemiology, University of Ioannina School of Medicine, Greece. He also took on numerous appointments in American medical schools, currently being Professor of Medicine and Director, Stanford Prevention Research Center, Stanford University School of Medicine.

This good professor and his team have shown again and again:

  • “that much of what biomedical researchers conclude in published studies—conclusions that doctors keep in mind when they prescribe antibiotics or blood-pressure medication … or when they recommend surgery for heart disease or back pain—is misleading, exaggerated, and often flat-out wrong”.
  • “that as much as 90 percent of the published medical information that doctors rely on is flawed”.
  • “that the field of medical research is so pervasively flawed, and so riddled with conflicts of interest, that it might be chronically resistant to change—or even to publicly admitting that there’s a problem”.

Click here to read more: David Freedman,The Altantic, November 2010.